Air pollution: An underestimated killer

A “PANDEMIC” of air pollution shortens lives worldwide by nearly three years on average, and causes 8.8 million premature deaths annually, scientists said on March 3.
Eliminating the toxic cocktail of molecules and lung-clogging particles cast off by burning oil, gas and coal would restore a full year of life expectancy, they reported in the journal Cardiovascular Research.
“Air pollution is a larger public health risk than tobacco smoking,” lead author Jos Lelieveld of the Max Planck Institute in Mainz, Germany, said.
“Much of it can be avoided by replacing fossil fuels with clean renewable energy.”
Compared to other causes of premature death, air pollution kills 19 times more people each year than malaria, nine times more than HIV/Aids, and three times more than alcohol, the study found.
Coronary heart disease and stroke account for almost half of those deaths, with lung diseases and other non-communicable diseases (NCDs), such as diabetes and high blood pressure, accounting for most of the rest.

Eliminating the toxic cocktail of molecules and lung-clogging particles cast off by burning oil, gas and coal, would restore a full year of life expectancy, say researchers — AFP

Only 6 per cent of deaths stemming from polluted air is due to lung cancer.
“Our results show there is an ‘air pollution pandemic’,” said senior author Thomas Munzel of the Max Planck Institute’s departments of chemistry and cardiology.
“Both air pollution and smoking are preventable, but over the past decades, much less attention has been paid to air pollution than to smoking, especially among cardiologists.”
The worst-hit region is Asia, where average lifespan is cut by 4.1 years in China, 3.9 years in India, and 3.8 years in Pakistan.
In some parts of these countries, toxic air takes an even steeper toll, other research has shown.
In India’s Uttar Pradesh state, which is home to 200 million people, small particle pollution by itself slashes life expectancy by 8.5 years, while in China’s Hebei Province (population of 74 million), the shortfall is nearly six years, according to the Air Quality Life Index, developed by researchers at the Energy Policy Institute of Chicago, United States.
African lives are also foreshortened by 3.1 years on average, with people in some nations – Chad, Sierra Leone, Central African Republic, Nigeria and Cote d’Ivoire – losing 4.5 to 7.3 years of life.
Among wealthier nations, the Soviet Union’s former satellite states have the deadliest pollution, especially in Bulgaria, Hungary and Romania.
“We show that about two-thirds of premature deaths are attributable to human-made pollution, mainly from fossil fuel use,” Munzel said.
“This goes up to 80 per cent in high-income countries,” he added. “5.5 million deaths worldwide a year are potentially avoidable.”
Double the deaths
Unavoidable excess mortality stems from natural dust storms, such as in central Asia and northern Africa, along with forest fires, though both phenomena are being amplified by manmade climate change, according to climate scientists.
The least-impacted regions of the world are the Americas, western and northern Europe, and small island states.
The figure of 8.8 million premature deaths from outdoor air pollution each year is double estimates from the World Health Organization (WHO).
“The impact of air pollution on cardiovascular and other NCDs was significantly underestimated,” Lelieveld explained, echoing a conclusion from other recent research.
Air pollution causes damage to the blood vessels through greater oxidative stress, leading to increases in blood pressure, diabetes, stroke, heart attacks and heart failure.
The revised number for China is 2.8 million premature deaths each year, two-and-a-half times the WHO estimates.
The researchers said there are signs in India, China and other emerging economies that people are growing intolerant of life-shortening toxic air.
“The realisation that air pollution is a major health risk can contribute to the willingness to phase-out fossil fuels, with the co-benefit of reducing climate warming,” Lelieveld said.
To assess the impact of air pollution on life expectancy, the researchers applied data on exposure to micro-particles (PM2.5) and ozone for the year 2015 to models that simulate how chemical processes in the atmosphere interact with natural and manmade pollutants, and data from the Global Burden of Disease.
Indoor pollution, mainly from cook stoves fuelled by biomass or coal, is also a major killer, but was not considered here. – AFP Relaxnews

Children’s Covid-19 cases not as severe

CHILDREN do not seem to be catching the virus in the same numbers as adults, and if they do, they are not developing severe symptoms, according to data from Chinese health officials.
Here’s what we know right now about the impact of the coronavirus on children.
Are children getting sick?
Yes, children are catching the coronavirus, but they’re generally developing mild cases of the illness.
Out of nearly 45,000 confirmed cases in China through Feb 11, there was only one death in someone younger than 20, according to the Chinese Center for Disease Control and Prevention, and no deaths among children younger than 10.
Out of 731 confirmed and 1412 suspected cases of Covid-19 in children in China, one child, a 14-year-old boy, died and nearly 6 per cent of cases were severe, compared with 18.5 per cent of adults experiencing severe symptoms, according to a new study that will be published in the journal Pediatrics in June. Also, only 6 per cent of cases were severe, compared with 18.5 per cent of adult cases.
Dr Arthur Reingold, an epidemiologist at the University of California at Berkeley, said the numbers show children carry the coronavirus but are not developing severe symptoms.
“The evidence so far would suggest that children, at least in China, many children have gotten infected and have … either had a very mild illness or not had any illness at all,” Reingold told CNN, adding that’s a pattern seen in many other respiratory viruses that are easily transmitted among children and by children.
There have been cases in the United States, similar to other countries, where children are getting sick. A high school student in Washington, a teenager in Georgia, an elementary school-age child in California and a three-year-old in Texas have all tested positive for the disease.

Children are catching the coronavirus, but they’re generally developing mild cases of the illness.

However, Reingold said, children are not developing as severe an illness from the coronavirus as older people.
“Children simply don’t get very sick when they get this infection,” he said. “So if they develop any symptoms at all, they’re mild … and so, severe illnesses and deaths, fortunately, are incredibly rare.”
Can children pass on the virus and what measures need to be taken?
Just because children are not as likely to develop major symptoms, or even any at all, does not mean they won’t contract the coronavirus. Reingold said it’s likely that the number of cases in children is underreported, in part because their symptoms are so minimal or mild, but he warned they can still infect others.
“We have to assume that they can spread it. They’re incredibly efficient at spreading other respiratory viruses like influenza. Of course, this is a different virus and it could be different,” Reingold told CNN. “But we assume that children are extremely efficient at spreading respiratory viruses, including the new Covid-19.”
The study in Pediatrics also showed strong evidence for human-to-human transmission, according to researchers. More than 90 per cent of all pediatric patients were either asymptomatic (4.4 per cent) or showed mild (50.9 per cent) or moderate (38.8 per cent) symptoms.”
The biggest concern is that in small or large groups, children could still pass along the virus to those who are more susceptible — including the elderly in the community or older family members.
So parents and children should take commonsense precautions recommended by the Centers for Disease Control and Prevention including regular hand cleaning with soap and water or alcohol-based hand sanitizers. Children and family members should engage in preventative measures to guard against spreading the respiratory infection, including covering coughs and staying up to date on vaccinations, according to the CDC.
School closings may also become more regular as community members test positive for the coronavirus. That would be one form of social distancing, just like a travel restriction, which officials hope can help contain the spread of the disease.
Reingold explained that historically, during previous outbreaks of the flu, including H1N1 in 2009, early school closures at least delayed the peak of the outbreak.
“You don’t prevent the outbreak, but you at least push it back a number of weeks,” he said. “But if you wait too long, then school closures don’t really have any demonstrable impact.”
This all presents challenges for parents, of course, who are trying to juggle their ability to work and care for their children, who may have to stay home if schools close. Reingold said alternatives such as day care or child care centers may experience similar levels of disease transmission as in schools.
But why aren’t children getting sick?
It’s not entirely known why children aren’t developing such severe cases.
“If they are getting infected and not getting sick, then it seems to me the most likely theory is that they do have some level of immunity, and most likely it’s from being exposed to other coronaviruses,” Reingold said.
Because smaller numbers of children have been infected with the coronavirus or only developed mild symptoms, it’s been more difficult to study the disease in the very young, according to a World Health Organization-China Joint Mission on Coronavirus Disease report in February. Without blood test results, “it is not possible to determine the extent of infection among children, what role children play in transmission, whether children are less susceptible or if they present differently clinically,” according to the report.
“We saw low attack rates in children and that is something that is important and warrants some further study,” said Dr Maria Van Kerkhove, the technical lead of the WHO’s Health Emergencies Program.
Infected children were generally identified through contact tracing in households of adults who were sick, according to the report.
Studying children with mild cases could be important to understanding why others are getting so sick, including the differences in children’s immune systems and underlying conditions in adults.
It could be that children don’t tend to have heart disease or lung disease or other conditions that make them vulnerable to getting very sick from coronavirus. Their immune systems could play a role, Reingold said.
“I think the other question, and this would be a theory, is that the immune response that you see is different, that children are still maturing in terms of their immune response and that somehow, beyond the issues of frailty and underlying diseases, they simply mount a different type of immune response,” he said. -CNN